Palace may have edged Liverpool in the Community Shield last month, but the Reds have dominated this fixture in the league for over a decade, with Liverpool winning nine of their last ten league visits to south London.
Liverpool will be without Hugo Ekitike, who received a red card in their midweek Carabao Cup match against Southampton.
Both teams are expected to create scoring opportunities, with Palace's Jean-Philippe Mateta and Liverpool's Mohamed Salah being key players to watch. Mateta has scored 29 goals in 55 Premier League appearances for Palace, while Salah has nine goals and five assists in 16 Premier League matches against Palace.
Selhurst Park has been a challenging ground for opposing teams, with Palace unbeaten in 11 league games heading into this match. However, Liverpool have scored first in eight of their last nine away games.
Given both teams' attacking capabilities and their recent form, a bet on both teams to score at 33/50 with Bet365 seems like a good option.
Another strong bet is on Mohamed Salah to score or assist, as he has a history of performing well against Palace and has been directly involved in five goals in his last six league games for Liverpool.
Jean-Philippe Mateta is also a good bet to have at least one shot on target, as he has played at least one shot on target in each of Palace's Premier League games this season.